Found 24 matching trials
AZD9291 First Time In Patients Ascending Dose Study PHASE1 This study will treat patients with advanced NSCLC who have already receive...
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Intracranial Activity of AZD9291 (TAGRISSO) in Advanced EGFRm NSCLC Patients With Asymptomatic Brain Metastases PHASE2 Patients will receive AZD9291 at a dose of 80 mg once daily. Intracranial r...
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Treatment Patterns, Outcomes and Testing in EGFRm NSCLC Patients With EGFR TKI 1L Across Europe (REFLECT) N/A Multinational, multi-center medical record review to describe the treatment...
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Resistance & Activating Mutations Diagnosed Among NSCLC Community Dwelling EGFR Mutation Positive Patients N/A The study is being done to determine if non-invasive testing (urine and pla...
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T790M Plasma Testing Methodology Comparison and Clinical Validation PHASE3 The aim of this study is to evaluate concordance of T790M mutation plasma t...
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Resistance to Oral Therapy in Lung Cancer N/A In the management of non-small cell lung cancer of the adenocarcinoma type,...
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University Hospital
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Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial) PHASE2 This phase II MATCH screening and multi-sub-trial studies how well treatmen...
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Active Not Recruiting
Location
University of Alabama at Birmingham Cancer Center
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AZD9291 in Combination With Ascending Doses of Novel Therapeutics PHASE1 The purpose of this study is to determine the safety, tolerability and prel...
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Active Not Recruiting
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A Study of Intermittent, High-dose Afatinib to Determine the Maximal Tolerated Dose and Assess Activity of This Dose Against Non-small Cell Lung Cancer With T790M Mutations PHASE1 This trial is divided into Part A and Part B. The primary objective of Part...
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Boehringer Ingelheim Investigational Site
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Safety, Tolerability and Pharmacokinetic Profile of BPI-15086 in EGFR T790M Mutation-positive NSCLC Patients PHASE1 The main objective of this study is to evaluate the safety and tolerability...
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Department of Medical Oncology, Cancer Institute/Hospital, Chinese Academy of Medical Sciences
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